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成份 · Ingredient
可比司他
可比司他是一種藥物動力學增強劑,主要用於HIV-1感染的治療。它透過抑制細胞色素P450酶系統來減緩其他抗病毒藥物的代謝,從而提高這些藥物的血液濃度和療效。本品不具直接抗病毒活性,而是作為輔助藥物使用。
Cobicistat is a monocarboxylic acid amide obtained by formal condensation of the carboxy group of (2S)-2-({[(2-isopropyl-1,3-thiazol-4-yl)methyl](methyl)carbamoyl}amino)-4-(morpholin-4-yl)butanoic acid with the amino group of 1,3-thiazol-5-ylmethyl [(2R,5R)-5-amino-1,6-diphenylhexan-2-yl]carbamate. Acts as a pharmacoenhancer in treatment of HIV-1 by inhibiting P450 enzymes that metabolise other medications.. It has a role as a P450 inhibitor. It is a carbamate ester, a monocarboxylic acid amide, a member of 1,3-thiazoles, a member of morpholines and a member of ureas.
| 藥品名稱 | 成份 | 號碼 |
|---|---|---|
| PREZCOBIX TABLETS 800MG/150MG | HK-64960 | |
| SYMTUZA TABLETS | HK-65912 |
藥品資料來源:香港衞生署藥物辦公室 · 化學資料來源:PubChem (NIH) · 資料僅供參考,不構成醫療建議