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成份 · Ingredient
阿莫羅芬
阿莫羅芬是一種嗎啉類抗真菌藥物，通過抑制真菌細胞膜合成中的多種酶（包括角鯊烯單加氧酶、Δ14-還原酶和Δ7-Δ8異構酶）來發揮作用。通常以鹽酸鹽形式用於局部治療真菌性指甲和皮膚感染，具有廣譜抗真菌活性。
Amorolfine is a member of the class of morpholines that is cis-2,6-dimethylmorpholine in which the hydrogen attached to the nitrogen is replaced by a racemic 2-methyl-3-[p-(2-methylbutan-2-yl)phenyl]propyl group. An inhibitor of the action of squalene monooxygenase, 14 reductase and D7-D8 isomerase and an antifungal agent, it is used (generally as its hydrochloride salt) for the topical treatment of fungal nail and skin infections. It has a role as an EC 1.14.13.132 (squalene monooxygenase) inhibitor, an EC 1.3.1.70 (Delta(14)-sterol reductase) inhibitor and an EC 5.3.3.5 (cholestenol Delta-isomerase) inhibitor. It is a tertiary amino compound and a morpholine antifungal drug. It is a conjugate base of an amorolfine(1+).
| 藥品名稱 | 成份 | 號碼 |
|---|---|---|
| ALIKANG NAIL LACQUER 5% W/V | HK-65486 | |
| AMOROLFINE NAIL LACQUER 5% W/V | HK-61679 | |
| AMOROLFINE SANDOZ NAIL LACQUER 5% W/V | HK-68364 | |
| CURAFEN NAIL LACQUER 5%W/V | HK-62654 | |
| CURANAIL NAIL LACQUER 5% W/V | HK-64406 | |
| DERMATOPIC CREAM 0.25%W/W | HK-63326 | |
| LAMOFIN NAIL LACQUER 5% W/V | HK-68691 | |
| LOCERYL CREAM 0.25%W/W | HK-51795 | |
| LOCERYL NAIL LACQUER 5% | HK-36522 | |
| LOMASYL CREAM 0.25% W/W | HK-68246 | |
| LOMORYL CREAM 2.5MG/G | HK-66253 | |
| LOMORYL NAIL LACQUER 5% W/V | HK-68692 | |
| NAIL CLEAR NAIL LACQUER 5%W/V | HK-63887 | |
| NAILCARE NAIL LACQUER 5%W/V | HK-62655 | |
| NAILGUARD NAIL LACQUER 5%W/V | HK-62689 | |
| NAILSOLUTION NAIL LACQUER 5%W/V | HK-62690 | |
| NAILTECH NAIL LACQUER 5%W/V | HK-63240 | |
| PHARMA AMOROLFINE NAIL LACQUER 5% W/V | HK-63856 | |
| PRONAIL NAIL LACQUER 5%W/V | HK-63241 | |
| ROMARYL CREAM 0.25%W/W | HK-63004 |
藥品資料來源：香港衞生署藥物辦公室 · 化學資料來源：PubChem (NIH) · 資料僅供參考，不構成醫療建議