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成份 · Ingredient
他法米迪
他法米迪是一種1,3-苯並噁唑類化合物,能夠穩定運甲狀腺素蛋白(TTR)四聚體結構,防止其解離和錯誤折疊形成澱粉樣蛋白沉積。主要用於治療運甲狀腺素蛋白相關的遺傳性澱粉樣變性病,包括心肌病變和周邊神經病變。
Tafamidis is a member of the class of 1,3-benzoxazoles that is 1,3-benzoxazole-6-carboxylic acid in which the hydrogen at position 2 is replaced by a 3,5-dichlorophenyl group. Used (as its meglumine salt) for the amelioration of transthyretin-related hereditary amyloidosis. It has a role as a central nervous system drug. It is a dichlorobenzene, a monocarboxylic acid and a member of 1,3-benzoxazoles. It is a conjugate acid of a tafamidis(1-).
藥品資料來源:香港衞生署藥物辦公室 · 化學資料來源:PubChem (NIH) · 資料僅供參考,不構成醫療建議